This comprehensive analysis confirmed substantial reductions in hepatic fat content measured by MRI-PDFF (weighted mean difference -5.8%, 95%CI: -7.1% to -4.5%), liver enzymes, and histological parameters including steatosis and inflammation scores
Eligibility required 13 prior lines including antiCD38 antibody and lenalidomide exposure, ECOG 02, and progression or nonresponse to the last regimen
Since clinical trials consistently show tirzepatide producing greater average weight loss than semaglutide, it might seem counterintuitive to switch in this direction
2 FINAL STUDY FINDINGS 2 As noted, use of semaglutide was associated with a 24% relative risk reduction for the primary outcome of major kidney disease events compared to treatment with placebo (HR 0.76
Alpha lipoic acid, along with several of the other antioxidants ALA helps to regenerate, detoxifies the body of heavy metals
We saw widespread shortages with Wegovy and Zepbound