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Factors that could spike more growth include GLP-1s pivot from premium injectables to high-volume chronic disease drugs, and that shift raises the bar for follow-on molecules

Major points for thoroughness though- I have the sense that if I ever have a question on future about diabetes the answer can be found here...though not necessarily very easily

The exacerbation of DR during puberty and pregnancy can be partially explained by the upregulation of VEGF and Ang-2, mediated by IGF-1 [14, 15, 27, 28], estrogen and progesterone [91, 92], in addition to hyperinsulinemia observed in both conditions

Shi, H-J

Insurers expect this will increase premiums by 4 percentage points more than otherwise would occur

10.1046/j.1365-4362.2002.01423.x Int J Dermatol