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Ultrastructural analysis by transmission electron microscopy further suggested that in the TB-500 group, the newly formed collagen fibrils tended to be thicker, with diameters extending up to around 87 nm, compared to a maximum of 62 nm in control tissue

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for diabetes as well as certain toxicological and pathological conditions of the liver

All of these interactions were beneficial for stabilizing the binding complexes

More patients have been diagnosed since the inclusion of lcFAODs in NBS panels, often before development of symptoms and it is debated whether dietary restrictions should be alleviated in certain patient groups [147, 148]