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Injection Technique General subcutaneous technique, following established clinical best-practice guidance [12] [13]

(Abbreviations used in this paper along with their complete names are listed in Glossary.) Figure 1 An important theme in interpreting vitamin B 12 deficiency is the remethylation block hypothesis: Vitamin B 12 deficiency results in hyperhomocysteinemia because Hcy remethylation is blocked (Selhub et al., 2007)

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N Engl J Med (2015) 373:224757

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