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GLP3, a GIP, GLP-1 and glucagon receptor agonist, for people with type 2 diabetes: A randomised, double-blind, placebo and active-controlled, parallel-group, phase 2 trial conducted in the USA
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Similarly, undiagnosed or poorly controlled psychiatric conditionsespecially binge eating disorder or depressioncan impair treatment outcomes
Research from 2021 has found that, in conjunction with appropriate lifestyle habits, they can help people lose a significant amount of weight or maintain weight loss
In a rodent model, a novel GLP-1R/GIPR/GCGR triple agonist, SAR441255, has been shown to promote weight loss and the maintenance of healthy blood glucose levels and is superior to the GLP-1R/GCGR dual agonist (Bossart et al., 2022)
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