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Drug Delivery and Translational Research, 9 (3), 625630
A total of 54% were Hispanic or Latino ethnicity
Delivered under the skin or into a muscle, bypassing the gut
Middleton D, Pallister J, Klein R, Feng YR, Haining J, Arkinstall R, et al
However, the largest Phase IIb trial involving 536 participants failed to demonstrate statistically significant weight loss compared to placebo at the primary 12-week endpoint, leading to development termination in 2007
The NHS Digital Weight Management Programme typically requires a BMI 30 kg/m (or 27.5 kg/m for certain ethnic groups) plus additional risk factors such as diabetes or hypertension
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