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The dosage starts at 2.5 mg once a week and is increased by 2.5 mg every four weeks, up to a maximum dose of 15 mg once weekly
Accumulation of ethanol-associated reactive molecules, e.g., reactive oxygen (ROS) and nitrogen species (RNS), and electrophilic products, e.g., acetaldehyde and lipid peroxidation-derived products, can be harmful to biological systems due to their propensity to inactivate enzymes, leading to loss of protein function, DNA damage and cell death 4
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Coordinate Solutions: The FDA collaborates with manufacturers to increase production, find alternative suppliers, and resolve issues that may be causing the shortage