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It is the job of the L cells to secrete GLP-1s and PYY to stimulate insulin secretion from the pancreatic beta cells, inhibit glucagon release, and slow gastric emptying after a meal

This physician-reviewed guide breaks down every major GLP-1 weight loss medication currently available comparing mechanisms, clinical results, side effects, dosing schedules, costs, and who each is best suited for

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It lacks the essential amino acid leucine that triggers muscle protein synthesis

Common side effects: Nausea Vomiting Diarrhea Constipation Mild abdominal discomfort Why side effects occur: These issues are most likely during the dose escalation phase, which is why the stepwise tirzepatide dosing schedule is so important

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