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It has been proposed that depletion of hepatic GSH, particularly mitochondrial GSH, is one of the early changes associated with chronic alcohol consumption and is a critical contributor to ALD pathogenesis 11

To create a ferritin complex, the nuclear receptor coactivator 4 (NCOA4) can attach to FTH1 directly

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Percentage of cell viability was expressed as (A sample A DMSO )/(A control A DMSO ) 100%