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Combination formulations may also have different pH optima for each component, forcing a compromise pH that may not be ideal for either peptide individually
Improvements in ALT and hepatic fat fraction were sustained up to 48 weeks of treatment with tropifexor, but dose-dependent pruritus was also the most common side effect (NCT02855164)
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Miller, Laurence J
The GO annotation results indicated that most differentially expressed CsGST genes were assigned to the protein binding GO term belonging to the biological process category, and few CsGST genes were assigned to the cell redox homeostasis GO term belonging to the molecular function category (Figure 5B
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