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"The FDA boxed warning tied to GLP-1 medications is specific to a rare cancer called medullary thyroid carcinoma
PMID: 34121137 Adam A
For hair growth, the relevant signaling pathways are: vascular stimulation (more blood flow to the dermal papilla), follicle repair (extending the anagen growth phase), inflammation modulation (calming the chronic low-grade inflammation that contributes to follicular miniaturization), and systemic growth signaling (IGF-1 levels that influence overall regenerative capacity)
Will recommend to colleagues
reduce heavy fried carbs
Consistent with these findings, previous in vitro studies showed that OXM is a full agonist at the GCGR and GLP-1R but is 3-fold less potent at the GCGR than native glucagon and 100-fold less potent at the GLP-1R than native GLP-1, in terms of activating cAMP accumulation ( Despite convincing data suggesting the central role of GLP-1R signalling in the food intake reduction effects of OXM, there were still some unexplained effects of the gut hormone including increased energy expenditure, suggesting a GLP-1R independent mechanism of action (35)
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