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The ferritins molecular properties, iron storage function and cellular regulation
Often called the master antioxidant, this molecule is naturally produced by your body and plays a critical role in cellular health
In this study, lipoxin A4 reportedly activated the ESR2/LPAR3/Nrf2 axis to reverse the downregulation of GPX4 in OA FLSs, thus antagonizing FLS ferroptosis and mitigating the pain and progression of KOA [140]
Research published in Redox Biology found that when cells were exposed to stress, older cells' glutathione levels plummeted to just 10% of their original levels, while younger cells maintained at least 35% of their glutathione
GillTWatlingSERichardsonJDMcCluskeyTTongJMeyerJHet al
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