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Most are familiar with insulin or metformin, but theres another class of drugs that are called glucagon-like peptide-1 receptor agonists, shortened to GLP-1 RAs or GLP-1s

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Across GLP-1 and incretin-based therapies, we are seeing outcomes beyond the scale: - fewer major cardiovascular events - kidney protection - improvements in conditions tightly linked to cardiometabolic dysfunction, including sleep apnea biology We should stop treating obesity as a cosmetic problem and start treating it like the systemic disease driver it is, across joints, heart, kidneys, and sleep

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Not only may there be a new pharmacotherapy for AUD, but the success of these drugs forces a reconceptualization of addiction itself

Discontinue use and seek emergency care if these occur