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GLP-1 receptors were expressed in normal thyroid tissues with inflammation, but not in normal thyroid tissues without inflammation

The weight loss difference between 1mg and 2mg is modest in diabetic patients, suggesting a plateau effect

The dual-agonist mechanism addresses both appetite suppression and glucose metabolism, making tirzepatide effective for patients with type 2 diabetes or metabolic syndrome alongside obesity

During fatty acid synthesis, the acyl groups of acetyl-CoA and malonyl-CoA are transferred to the sulfhydryl group (-SH) of the 4-phosphopantetheinyl moiety of ACP

The ultra-prescient Scott Galloway predicted in late 2023 that GLP-1s would be bigger than GPT (#AI) and that ripple effects would affect the likes of Walmart and McDonalds

[PMID: 39480409] PubMed record related to this compound for laboratory literature review