The dose may need to be re-evaluated after 6-12 months, but again, this is based on observed symptoms, not predictions
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Pourmand G, Movahedin M, Dehghani S, Mehrsai A, Ahmadi A, Pourhosein M, Hoseini M, Ziloochi M, Heidari F, Beladi L, Noori M
6, June 2007, pp
Once patients have the opportunity to enroll in a clinical trial, multiple barriers complicate patient acceptance and subsequent enrollment
To reduce these potential risks, healthcare providers are advised to closely monitor patients, particularly those with a history of gallbladder or biliary disease [49]