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Glutathione synthetase deficiency is the most frequently recognized disorder and, in its severe form, it is associated with hemolytic anemia, metabolic acidosis, 5-oxoprolinuria, central nervous system (CNS) damage and recurrent bacterial infections

Salinomycin, a potent inhibitor of XOD and URAT1, ameliorates hyperuricemic nephropathy by activating NRF2, modulating the gut microbiota, and promoting SCFA production

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Adequate hydration should be emphasised, and blood pressure should be monitored, especially during treatment initiation

reported that Diane-35 decreased serum testosterone levels in PCOS patients [Citation14]

Tirzepatide is administered through a once-weekly subcutaneous injection in the abdomen, thigh, or upper arm