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Liraglutide improves cardiac function in patients with type 2 diabetes and chronic heart failure

Gastrointestinal side effects represent one of the most common challenges when starting GLP-1 receptor agonist therapy, with diarrhea occurring in approximately one-quarter of patients during initial dose escalation

In recent years, Novo Nordisks injectable Wegovy and Lillys Zepbound have revolutionised obesity treatment globally and in the U.S., where 100 million people have the chronic disease

Researchers enrolled 17,604 adults who: were 45 years or older had overweight or obesity (BMI 27) already had heart disease (such as a prior heart attack, stroke, or peripheral artery disease) did not have diabetes Participants were randomly assigned to receive either: semaglutide 2.4 mg weekly, or a placebo (an injection with no active medication) They were followed for about 40 months (over 3 years)

Its a well-established, first-line treatment for controlling blood sugar levels in people with type 2 diabetes

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