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Previously, it has been shown that mechanotransduction and cytoskeletal dynamics can fine-tune metabolic pathways 23

doi: 152

When to seek medical advice : Patients should contact their GP or prescribing clinician if they experience: Lumps that are enlarging, increasingly painful, or not resolving after several weeks Signs of infection (increasing redness, warmth, purulent discharge, fever) Systemic symptoms such as malaise or fever Persistent bleeding or bruising at injection sites For urgent concerns that are not life-threatening, contact NHS 111 for advice

Most individuals start to experience positive changes within the first week, with optimal results developing over two to four weeks of consistent use

Understanding this helps contextualize the temporary worsening some researchers experience