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This paper reports the discovery that hyperactivation of the PI3KAKT pathway can sensitize cancer cells to oxidative stress owing to the inactivation of FOXO factors and the resulting decrease in the expression of antioxidant enzymes

PubMed, doi:10.1200/JCO.18.02202.Barakat, Radwa, et al

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The Science of Pain Relief: How It Works Understanding the biology behind acupuncture helps explain why this treatment produces real results for sciatica sufferers