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Description

2017;43(Suppl 1):2S139

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Dosage: Oral dosage is to be taken every day

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Exenetide (Bydureon BCise) Exenetide is the oldest of the GLP-1 agonists approved to treat type 2 diabetes

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Lead series optimization Our goal was to enhance interactions of the small-molecule agonists with the GLP-1R through lowering the energy barrier to achieve the receptor-bound agonist conformation, and by adjusting polar substituents, with minimal increases in molecular weight

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Most people who are on GLP-1 medications experience at least one side effect

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10.1007/BF02408436 44

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