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[1] Additionally, the authors indicate that there is still a requirement for successful human trials to be completed prior to clinical translation as there are important differences between rodent and human physiology that could have a significant impact on the efficacy and safety of any agent

The clinical development program has demonstrated unprecedented efficacy that exceeds any currently available obesity pharmacotherapy

No, direct causal link has been established in the research literature

Most people notice initial effects within the first few weeks, with more significant results appearing over several months

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Plus, most claimed benefits are based on animal studies, early research, or anecdotal reports, rather than strong human clinical evidence