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Among these drugs, glucagon-like peptide (GLP-1) drugs are strongly recommended by major diabetes treatment guidelines for their glucose-lowering effects, as well as for their weight-lowering, blood pressure-lowering, cardiovascular and renal protective effects
Although ACTL6A has been characterized as an oncogene in many human cancers, its role in GC is unknown, and knowledge of the underlying mechanisms is limited
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These secondary messengers are hypothesized to increase calcium release from intracellular stores and activate protein kinase C (PKC), together contributing to vesicular secretion from somatotroph cells
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