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Despite its favorable profile, caution should be exercised when administering it to patients as careful monitoring of individual factors remains vital in ensuring optimal safety and efficacy when using this therapy for musculoskeletal conditions like tendonitis

Vitamin B12 metabolism and massive-dose methyl vitamin B12 therapy in Japanese patients with multiple sclerosis

Ouwendijk et al., 2021)

Consequently, therapeutic strategies targeting PRRs primarily involve the use of ligand analogs to activate these receptors, 577 using antagonists to block their activation, or using antibodies and small molecules to inhibit PRR signaling pathways

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