Hartman, MD, a board-certified dermatologist and founder of Skin Wellness Dermatology based in Birmingham, Alabama Jenna Queller, MD, a board-certified dermatologist based in Boca Raton, Florida
In one clinical trial, nearly 14% of participants did not lose a clinically meaningful amount of body weight at least 5% after more than one year of taking semaglutide 3
How Fiber Triggers GLP-1 When soluble fiber reaches your colon, gut bacteria ferment it into short-chain fatty acids (SCFAs) particularly butyrate, propionate, and acetate
Remove the Needle and Dispose of It Safely Once the injection is complete, carefully remove the needle and place it into a sharps container for safe disposal
But clinical trials have limitations
The net result is a measurable shift in appetites and diet patterns resulting in less processed food, and greater consumption of nutritionally dense, unprocessed items (Dilley et al., 2025)