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R.R., Z.Y., S.L., G.Z., and S.H
Preclinical and observational data suggested possible benefits, spurring rigorous clinical testing
To put it simply, if a GLP-1 or triple G-agonist even got rid of insulin requirement in 1 out of 10 new onset Type 1 diabetics, that would be a very big deal
At least 4 distinct inhibitors have been identified, of which the plasminogen activator-inhibitors type 1 ( PAI-1 ) and type 2 ( PAI-2 ) are of greatest physiological significance
India is home to over 100 million people with diabetes and approximately 250 million classified as obese or overweight.[15] What makes the situation uniquely dangerous is the Thin-Fat Indian paradox: South Asians tend to accumulate more visceral (belly) fat, liver fat, and less lean muscle mass at lower body weights than Western populations.[8][9][10] While GLP-1 medications are a global phenomenon, they are particularly critical for the Thin-Fat Indian phenotype
J Neurol Sci
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