Pathways of Gastric Carcinogenesis, Helicobacter pylori Virulence and Interactions with Antioxidant Systems, Vitamin C and Phytochemicals
While well-tolerated, they require careful consideration of potential adverse effects and contraindications (6)
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So if we were to inhibit the SLC33A1 transporter, the GSSG would accumulate, and the cancer cells would die. Our work demonstrates that defining how nutrients and metabolites are transported across cellular and organelle membranes reveals fundamental principles of cell biology while uncovering a major class of disease-relevant and therapeutically tractable proteins, Birsoy says
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Willcox DC, Scapagnini G, Willcox BJ