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Simultaneously, we observed a decrease in serum creatinine and triglyceride expression after rhein treatment, suggesting that rhein can improve lipid metabolism and protect kidney function in ORG mice (Figure 2B)

B 12 and BV binding measurements The binding ratio of B 12 and BV ligands was calculated based on their extinction coefficient

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Furthermore, this trend toward increased alpha diversity in the obese groups placed on an LD that had consequently experienced weight loss aligns with clinical observations, where low gene richness has been associated with increased adiposity, insulin resistance, and dyslipidemia 70 while increased gene richness has been observed following dietary intervention in obese and overweight individuals 71

While the BUD on the label tells you how long the unopened vial is good for, a different rule often applies once the vial has been used for the first time