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Because of the low toxicity of vitamin B 12 , no tolerable upper intake level (UL) has been set by the US Food and Nutrition Board (21)

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It is clinically employed as an adjunct therapy in infectious diseases, cancers, and immunodeficiency conditions due to its ability to stimulate T cell maturation and modulate both innate and adaptive immune responses 1,3,4

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doi: 10.1016/j.metabol.2024.155998

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