The authors conclude: In this real-world study where half of patients discontinued GLP-1-based treatment within a year after initiation, not losing weight was associated with worse clinical outcomes while larger reductions were associated with decreased risks
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The Gut Zoomer evaluates bacterial diversity, commensal balance, pathogenic overgrowth, digestive capacity, and markers of barrier function such as zonulin and calprotectin
Finally, ratio of emission intensities of the donor and acceptor fluorescent proteins (FRET ratio) reports dynamics of level of the target metabolite
1,6 Despite normal secretion of GLP-1 and GIP, the incretin effect is reduced or absent in people with type 2 diabetes, with the insulin-stimulating effect of GIP being more impaired when compared to GLP-1
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