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However, in senescent CD8 T cells, autophagy is not restored despite reduced mTORC1 activity, partly due to alternative inhibitory mechanisms such as chronic p38 MAPK activation, which impairs autophagy independently of mTORC1 and contributes to immune decline in senescent CD8 T cells

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Krystal JH, Moghaddam B

Consult your GP if you have diabetes, take warfarin, or are on multiple medications, as interactions may occur

Dihexa is generally well tolerated when used under medical supervision, and most people report few side effects