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10.1016/J.IJFOODMICRO.2010.08.008 Int

Unfortunately no control group, but I guess we assume each person is their own control and with 6+ months of amenorrhea likelihood of natural cycles returning without any change in habits is low

This can affect accessibility and cost for patients seeking weight loss-specific drugs

A second mechanism of PKA-independent incretin potentiation of glucose-stimulated insulin secretion (GSIS) involves cAMP-regulated guanine nucleotide exchange factor (cAMP-GEF) EPAC2

Back Ceranowicz, P, Cieszkowski, J, Warzecha, Z, et al (9 June 2015) 'The beginnings of pancreatology as a field of experimental and clinical medicine', Biomedical Research International , 2015, 128095

Changes are made based on symptoms or weight