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Al-Majed and colleagues [140] found that carnitine deficiency and oxidative stress are risk factors during development of cisplatin (CDDP)-induced cardiomyopathy and that carnitine supplementation, using propionyl-l-carnitine, prevents the progression of CDDP-induced cardiotoxicity
Genetic testing of the expecting parents (and related family members) and prenatal diagnosis (molecular testing of the fetus during pregnancy) may help in understanding the risks better during pregnancy If there is a family history of the condition, then genetic counseling will help assess risks, before planning for a child Active research is currently being performed to explore the possibilities for treatment and prevention of inherited and acquired genetic disorders The prevention of Secondary Carnitine Deficiency Syndrome involves suitably treating the underlying metabolic disorder with which it is associated
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The severity of these symptoms is mainly mild to moderate, and they are most prominent at treatment initiation and intensification (44)
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