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This can be especially beneficial for individuals with joint pain or those undergoing rigorous training regimens that put stress on their joints

Curated data place Melanotan 1 as a full agonist at four subtypes with a clear order-of-magnitude preference for MC1R: pIC 10.0 at MC1R, pKi 8.9 at MC3R, pKi 8.5 to 8.8 at MC4R, pIC 9.0 at MC5R, and no activity at MC2R

When choosing between these treatments, its important to weigh the cost against the expected benefits and outcomes