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The progression of CKD can lead to end-stage renal disease (ESRD), increasing the risk of kidney failure with a need for renal replacement therapy involving dialysis or renal transplant

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Can glutathione IV therapy be combined with other treatments

GSH is one of the body's principal antioxidant defense molecules, playing a crucial role in the detoxification of cytotoxic compounds and reactive oxygen species.10 Intracellular GSH concentrations differ among tissues, typically ranging from 1 to 10 mM, with the highest levels observed in the liver.11 Experimental supplementation of GSH in animal models has been shown to reduce hepatocyte apoptosis, lower plasma AST and ALT activities, and protect against microvascular reperfusion injury.12 Melatonin (Mel) is a hormone primarily secreted by the pineal gland, but it is also synthesized in various tissues, including the ovaries, retina, lens, bone marrow, and gastrointestinal tract.13 In the retina and gastrointestinal system, it plays roles in visual adaptation and oxidative protection, respectively

Mild Side Effects Side effects may include nausea, vomiting, diarrhea, constipation, abdominal pain, fatigue, dizziness, and hypoglycemia

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