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This increased risk is commonly seen among patients with diabetes and is in connection with worsened clinical conditions and higher mortality in patients with acute ischemic stroke (AIS)
Interestingly, certain bitter compounds, such as denatonium benzoate (DB), have been found to stimulate the secretion of insulin, glucagon, somatostatin, and GLP-1 from pancreatic islets independently of glucose levels
Malone, M
Feng, X., Li, L., & Zhang, Y
Concurrently, the glucose-lowering strategy has evolved from solely managing hyperglycemia to emphasizing comprehensive, long-term patient benefits
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