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The disadvantage is shorter shelf life (the clock starts from the pharmacy compounding date, not your reconstitution date), higher cost per milligram, and no ability to customize concentration

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Studies indicate that in the presence of insulin, GIP enhances phosphorylation of protein kinase B (PKB/Akt) and inhibits phosphorylation of LKB1 and AMPK, leading to activation of lipoprotein lipase (LPL) and lipid accumulation

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