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doi: 10.1093/eurheartj/ehy036 6
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The ACC also supports the use of GLP-1R agonists for cardiovascular risk reduction in patients with T2DM and multiple ASCVD risk factors, independent of glucose control or background antihyperglycemic therapy [122]
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An agonist activates a receptor
Accordingly, incretin-based therapies, such as DPP-4 inhibitors and GLP-1 receptor agonists (GLP-1 RAs) that are resistant to degradation by DPP-4, have been introduced in the market within the past decade to overcome and extend the short half-life of the incretin effect
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