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Following the Ozempic active ingredient's patent expiration in late March, the company is introducing generic semaglutide injections in India
In the STEP-HFpEF (Semaglutide Treatment Effect in People with Obesity and HFpEF) program, the glucagon-like peptide-1 receptor agonist (GLP-1RA) semaglutide, at a weight-management dose of 2.4 mg once weekly, reduced heart failure (HF)related symptoms, physical limitations, and body weight in patients with obesity-related heart failure with preserved ejection fraction (HFpEF)
This suggests that while pharmacotherapy amplifies initial outcomes, structured exercise is strongly associated with more durable weight-loss maintenance
Endocrinology 155:12801290
Happy to see more clinicians pushing toward comprehensive care
Wegovy should be used with a reduced calorie meal plan and increased physical activity
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