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That occurs in patients losing significant weight on tirzepatide therapy

In the SURMOUNT-1 trial (Jastreboff et al., NEJM 2022), mean weight loss at 72 weeks varied by dose: 15.0% at 5 mg, 19.5% at 10 mg, and 22.5% at 15 mg

This denatures the peptides molecular structure, rendering it inactive

Complementary treatments : We may recommend additional treatments like WONDERBOD to help maintain muscle mass during weight loss

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