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This synergistic effect is the basis for dual GIP/GLP-1 agonists (like tirzepatide), but selective GIP agonists allow researchers to investigate the specific contribution of GIP agonism when combined with GLP-1 agonism, isolating GIP's synergistic potential

This new option has been welcomed in the fight against obesity in the U.S

Though information is scarce, a review of the literature did show some improvements in sperm density, motility, and morphology in 2 small studies

Farrokhi Yekta R, Rezaie Tavirani M, Arefi Oskouie A, Mohajeri-Tehrani MR, Soroush AR

May stimulate proteoglycan synthesis though direct cartilage regeneration evidence limited

Peripheral neuropathy may take 36 months to improve, and some patients experience incomplete recovery, particularly if treatment was delayed