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In a Phase IIb trial of 320 adults with obesity and biopsy-confirmed MASH and fibrosis stages F1F3, subcutaneous semaglutide (0.1 mg, 0.2 mg or 0.4 mg daily for 72 weeks) resulted in a significantly higher proportion of participants with MASH resolution without worsening of fibrosis than placebo (40%, 36% and 59% in participants treated with 0.1 mg, 0.2 mg or 0.4 mg daily, respectively, compared with 17% in the placebo group)
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"Yet, this population is much less likely to be included in clinical trials or be treated with medications that have proven benefits," said Lingvay, a professor of internal medicine at UT Southwestern
The article links contaminated medication to injection-site infections, abscess formation, and systemic inflammatory responses
Glutathione effectively eliminates free radicals by interrupting oxidation-reduction reactions
doi:10.1007/978-94-007-7500-8_9
