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DSIP vs Epithalon: two different mechanisms, two different patients Delta Sleep-Inducing Peptide (DSIP) is a neuropeptide that acts directly on sleep centers in the brain to initiate sleep onset and increase non-REM sleep time

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The very low rate constants for direct, glutathione-independent dithiol-disulfide exchange reactions between glutaredoxins and roGFP2 or other protein(S 2 )/protein(SH) 2 couples (despite favorable thermodynamics) are a prerequisite and great advantage for reliable redox measurements in vivo

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