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The DONEPEZOX trial, as a proof-of-concept, randomized, triple-blind, and multicenter study, will be the first clinical trial to evaluate the efficacy and safety of donepezil in oxaliplatin for gastrointestinal cancer-induced severe peripheral neuropathy (OIPN), with the response rate in the donepezil group (neuropathy grade reduction according to the QLQ-CIPN20 sensory score) as the primary endpoint [168]
By modernizing policy, #Ohio can unlock millions in health and economic benefits while strengthening our workforce and communities
13 Although results from the five studies are mixed, the overall evidence suggests a possible benefit of NAC in children with ASD, at a dose of at least 600 mg per day for at least 8 weeks
[28] The resistance of lipedema tissue to conventional weight loss methods has prompted investigation into pharmacological approaches
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