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Adjunct Associate Professor Khoo Chin Meng, head and senior consultant at National University Hospitals division of endocrinology, said the ingredients used to make them are largely unknown

To digest and remove any traces of Matrigel, the suspension was centrifuged (300 x g , 5 mins, 4 C), 350 L of TrypLE Express (Gibco) was added to the spheroid pellets and incubated in a 37 C water bath for 3 mins

These side effects were usually mild or moderate, often improved with time, and only a small number of participants stopped treatment because of them

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First, the delivery method is problematic