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Evaluation of Acute Toxicity and the Effect of Single Injected Doses of Zerumbone on the Kidney and Liver Functions in Sprague Dawley Rats

Less common side effects include flushing, headache, or nausea

The sample was vigorously shaken on an MX-F vortex mixer (Dragon Laboratory Instruments Ltd., Beijing, China) for 1 min before dissolution by an ultrasonicate (Kunshan Ultrasonic Instruments Co., Ltd., Kunshan, China) for 20 min

The samples were washed three times with PBS, each time for 5 min

FDA staff reviewers raised these same evidence gaps during the July 2026 advisory committee hearing, specifically citing insufficient data to support efficacy claims for some proposed uses

Lyophilization, or freeze-drying, is the gold standard for preserving the intricate structure of peptides like BPC 157 Peptide