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At 12 months, weight loss persisted at around 4%, with variability between agents, most notably liraglutide
336 In 60 patients with treatment-resistant depression, adding 25 mg zinc daily to treatment with the tricyclic antidepressant imipramine (Tofranil) for 12 weeks led to a more rapid and robust treatment response compared with placebo
Alternative metrics such as waist circumference, body composition analysis, or progress photographs provide better assessment of treatment efficacy
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Intrathecal injection of exenatide (1-100 ng) elicited dose-dependent antinociception in formalin-induced tonic flinching responses without affecting acute nociceptive phases [24] (Fig
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