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Peptides are short chains of amino acids connected by peptide bonds, and they function as vital signaling molecules

Conclusion Is It Worth the Risk

The right question is not does the oral route achieve high bioavailability? but does the oral route deliver the peptide to its intended target? For a systemic target, oral delivery is a hard pharmaceutical engineering problem

Incorporating in vivo pharmacokinetic data or clinical evidence would enhance scientific rigor

Recently, it has been reported that aberrant activation of the cGAS-STING pathway contributes to the development of fibrotic lung diseases [112]

The absolute concentrations of GSS and GSH were then normalized to the migration length of the Schirmers strip (tear fluid volume) and the dilution factor (extraction buffer volume)