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Semaglutide may slightly increase ED risk in some groups

Sophie Dix (BSc, PhD) Published: 20 August 2024 | Updated: 25 July 2026 Updated: 25 July 2026 Reading time: 9 minutes Quick navigation: Article Summary: What is Wegovy and how does it work

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Nevertheless, tirzepatide use seemed to be associated with a higher risk (RR 1.97, 95% CI 1.143.42, p = 0.558) [129]

First, it can impair the transport of long-chain fatty acids into the mitochondrial matrix, with subsequent decrease in -oxidation, acetyl-CoA and ATP production