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Description

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This review provides a synthesis of the current understanding of lactate and lactylation in tumor immunosuppression, detailing molecular mechanisms underlying immune cell inhibition (tumor-associated macrophages, T cells, T-reg cells, NK cells and NKT cells, as well as neutrophils) and evaluating emerging therapeutic strategies ( e.g

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The antibodies used include anti-D2R (Santa Cruz Biotechnology, mouse, catalogue# sc-5303) and anti-DAT (Santa Cruz Biotechnology, rat, catalogue# sc-32258)

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