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The absence of nutrient diversity, imbalanced macronutrient intake and decreased phytochemical intake can lead to a loss of gut microbial diversity, including keystone bacteria, and simultaneously increased growth of opportunistic species, contributing to subsequent dysbiosis, reduced short-chain fatty acid (SCFAs) production, and inflammation
It plays a significant role in promoting moderate mitochondrial stress, which activates Nrf2, adenosine 5-monophosphate-activated protein kinase (AMPK), and SIRT1 and SIRT3, all of which are involved in anti-inflammatory and antioxidant responses (188)
Proc Natl Acad Sci USA 97:1438214387 Philip P, Sagaspe P, Taillard J et al (2019) Acute intake of a grape and blueberry polyphenol-rich extract ameliorates cognitive performance in healthy young adults during a sustained cognitive effort
Your next phase may include an adjusted schedule and integration into your broader care program based on your goals and progress
The use of hyperaccumulator plants [107] which can accumulate heavy metals in the leaves at 100-fold higher concentration than normal plant species can be the alternative solution to clean-up polluted soils
